Hemorrhage Risk in Moyamoya Disease with Fetal-Type Posterior Cerebral Artery: A Propensity Score-Matched Analysis

World Neurosurg. 2023 Dec:180:e30-e36. doi: 10.1016/j.wneu.2023.07.025. Epub 2023 Sep 9.

Abstract

Objective: Patients with moyamoya disease (MMD) and fetal-type posterior cerebral arteries have not been thoroughly investigated as yet. We focused on the risk of intracranial hemorrhage in patients with MMD and fetal-type posterior cerebral arteries.

Methods: We reviewed 2422 patients with MMD diagnosed at the Neurosurgical Department of Beijing Tiantan Hospital between May 2009 and December 2020. We classified patients into 2 groups according to whether they had a fetal-type posterior cerebral artery. After 1:1 propensity score matching, hemorrhagic tendency and Suzuki stage were compared between patients with a fetal-type posterior cerebral artery (group I) and patients without a fetal-type posterior cerebral artery (group II).

Results: In total, 2415 patients were included in this study; 181 had fetal-type posterior cerebral arteries. Hemorrhagic events were more frequently observed in patients with fetal-type posterior cerebral artery development than in those without it (28.2% vs. 18.8%, P = 0.035). However, Suzuki stages did not differ between the 2 matched groups (4.03 vs. 4.20, P = 0.081).

Conclusions: Hemorrhagic events occurred more frequently in patients with MMD with fetal-type posterior cerebral arteries than in those without.

Keywords: Computed tomography angiography; Digital subtraction angiography; Fetal-type posterior cerebral artery; Hemorrhage; Moyamoya disease.

Publication types

  • Review

MeSH terms

  • Cerebral Angiography
  • Cerebral Hemorrhage / diagnostic imaging
  • Cerebral Hemorrhage / epidemiology
  • Cerebral Hemorrhage / etiology
  • Cerebral Revascularization*
  • Humans
  • Intracranial Hemorrhages
  • Moyamoya Disease* / complications
  • Moyamoya Disease* / diagnostic imaging
  • Moyamoya Disease* / surgery
  • Posterior Cerebral Artery / diagnostic imaging
  • Posterior Cerebral Artery / surgery
  • Propensity Score
  • Retrospective Studies

Supplementary concepts

  • Moyamoya disease 1