Brain mitochondria in behavior: more than a powerhouse

Trends Endocrinol Metab. 2024 Jan;35(1):1-3. doi: 10.1016/j.tem.2023.09.008. Epub 2023 Oct 5.

Abstract

Rosenberg and colleagues developed a miniaturized assay of mitochondrial content and energy transformation capacity that allowed them to assess mitochondrial features and activities across the brain in male mice. Their findings provide a comprehensive brain-wide map of mitochondrial associations with stress-induced behaviors and highlight mitochondria as dynamic, spatially-organized organelles.

Keywords: behavior; brain bioenergetics; mitochondria; stress.

MeSH terms

  • Animals
  • Brain*
  • Energy Metabolism
  • Male
  • Mice
  • Mitochondria* / metabolism