Gleason Grade Group 4 prostate biopsy with no cancer seen on final pathology in the magnetic resonance imaging and Prostate Specific Membrane Antigen-Positron Emission Tomography era

Nikhile Mookerji; Rohan Mittal; Amaris Hui; Tyler Pfanner; Stacey Broomfield; Luke Dean; Benjamin Adam; Christopher Fung; Alexander Tamm; Adam Kinnaird

doi:10.1002/iju5.12614

Gleason Grade Group 4 prostate biopsy with no cancer seen on final pathology in the magnetic resonance imaging and Prostate Specific Membrane Antigen-Positron Emission Tomography era

IJU Case Rep. 2023 Aug 11;6(6):337-340. doi: 10.1002/iju5.12614. eCollection 2023 Nov.

Authors

Nikhile Mookerji¹, Rohan Mittal², Amaris Hui³, Tyler Pfanner³, Stacey Broomfield¹, Luke Dean¹, Benjamin Adam², Christopher Fung³, Alexander Tamm³, Adam Kinnaird^{1

4

5

6

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Affiliations

¹ Division of Urology, Department of Surgery University of Alberta Edmonton Alberta Canada.
² Department of Pathology University of Alberta Edmonton Alberta Canada.
³ Department of Radiology & Diagnostic Imaging University of Alberta Edmonton Alberta Canada.
⁴ Alberta Prostate Cancer Research Initiative (APCaRI) Edmonton Alberta Canada.
⁵ Cancer Research Institute of Northern Alberta (CRINA) Edmonton Alberta Canada.
⁶ Alberta Centre for Urologic Research and Excellence (ACURE) Edmonton Alberta Canada.
⁷ Department of Oncology University of Alberta Edmonton Alberta Canada.

Abstract

Introduction: The absence of prostate cancer on final surgical pathology after biopsy-proven prostate cancer is a rare finding.

Case presentation: Case of pT0 prostate cancer following Gleason Grade Group 4 in 1 out of 12 cores from a transrectal ultrasound-guided biopsy in a man who underwent both magnetic resonance imaging and ¹⁸F-PSMA-1007 Positron Emission Tomography prior to radical prostatectomy.

Conclusion: pT0 prostate cancer is rare. The use of novel imaging modalities may help in the workup of prostate cancer.

Keywords: PSMA PET; multiparametric MRI; prostate cancer; vanishing cancer.

Publication types

Case Reports