Keywords: BMP6; Dynein light chain Tctex-type 3; Dynlt3; LRP5; LRP6; Monoclonal; Pathway; RANKL; Romosozumab; Signaling; Wnt; activity; adverse effect; antibody; bone morphogenetic protein 6; flare; injection; low-density lipoprotein receptor-related protein 5; low-density lipoprotein receptor-related protein 6; medication; osteoporosis; progression; receptor activator of nuclear factor κB ligand; sclerostin; vitiligo; ß-catenin.