Antibiotic nanoparticles boost antitumor immunity

Nat Biotechnol. 2024 Aug;42(8):1187-1188. doi: 10.1038/s41587-023-02046-6.

Kai Han^#^{1

2

3}, Young Seok Cho^#^{1

3}, James J Moon^{4

5

6}

¹ Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI, USA.
² State Key Laboratory of Natural Medicines, Department of Pharmaceutics, China Pharmaceutical University, Nanjing, China.
³ Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.
⁴ Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI, USA. moonjj@umich.edu.
⁵ Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA. moonjj@umich.edu.
⁶ Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA. moonjj@umich.edu.

^# Contributed equally.

Abstract

Liposomes loaded with antibiotics eliminate intracellular bacteria in a colorectal cancer model, unleashing antitumor T cell immunity.