Women's Health and Pregnancy in Multiple Sclerosis

Neurol Clin. 2024 Feb;42(1):275-293. doi: 10.1016/j.ncl.2023.07.004. Epub 2023 Aug 17.

Abstract

Multiple sclerosis has a 3:1 female-to-male predominance and commonly presents in young adult women. The hormonal changes in women throughout their lifetime do affect the underlying pathology of multiple sclerosis, and the needs of women therefore change with age. Although multiple sclerosis does not adversely affect fertility or pregnancy, there are many factors to consider when caring for women throughout family planning, pregnancy, and the postpartum period. The care of these women and complex decisions regarding disease-modifying therapy use in family planning should be individualized and comprehensive.

Keywords: Disease-modifying therapies; Multiple sclerosis; Neuroimmunology; Pregnancy; Women’s health.

Publication types

  • Review

MeSH terms

  • Female
  • Humans
  • Male
  • Multiple Sclerosis* / complications
  • Multiple Sclerosis* / epidemiology
  • Multiple Sclerosis* / therapy
  • Postpartum Period
  • Pregnancy
  • Women's Health
  • Young Adult