Olfaction: an emerging regulator of longevity and metabolism

Abstract

Ageing is a malleable process influenced by the environment. Recent research reveals that neurons interact with peripheral organs to regulate metabolism and longevity by responding to olfactory cues through specific pathways, such as the unfolded protein response (UPR) and microRNAs. Here, we examine the significance of these findings.

Keywords: environmental cues; longevity; odorants; proteostasis; stress responses.