MRI of cerebral oedema in ischaemic stroke and its current use in routine clinical practice

Neuroradiology. 2024 Mar;66(3):305-315. doi: 10.1007/s00234-023-03262-2. Epub 2023 Dec 16.

Abstract

Currently, with the knowledge of the role of collateral circulation in the development of cerebral ischaemia, traditional therapeutic windows are being prolonged, with time not being the only criterion. Instead, a more personalised approach is applied to select additional patients who might benefit from active treatment. This review briefly describes the current knowledge of the pathophysiology of the development of early ischaemic changes, the capabilities of MRI to depict such changes, and the basics of the routinely used imaging techniques broadly available for the assessment of individual phases of cerebral ischaemia, and summarises the possible clinical use of routine MR imaging, including patient selection for active treatment and assessment of the outcome on the basis of imaging.

Keywords: DWI-ASPECTS; DWI-FLAIR mismatch; Ischaemic stroke.

Publication types

  • Review

MeSH terms

  • Brain Edema*
  • Brain Ischemia* / diagnostic imaging
  • Brain Ischemia* / therapy
  • Cerebral Infarction
  • Diffusion Magnetic Resonance Imaging / methods
  • Humans
  • Ischemic Stroke*
  • Magnetic Resonance Imaging
  • Stroke* / diagnostic imaging
  • Stroke* / therapy