Ruxolitinib for Refractory PL-12 Antisynthetase Syndrome-Associated Angioedema-Like Panniculitis With Clonal T-Cell Receptor Gene Rearrangement

JAMA Dermatol. 2024 Mar 1;160(3):363-366. doi: 10.1001/jamadermatol.2023.4940.
No abstract available

Plain language summary

This case report describes a woman in her 30s who presented with a 3-year history of anti–PL-12 antisynthetase syndrome characterized by interstitial lung disease, arthritis, and myositis and was diagnosed with antisynthetase syndrome–associated panniculitis.

MeSH terms

  • Antibodies, Antinuclear
  • Autoantibodies
  • Genes, T-Cell Receptor
  • Humans
  • Myositis* / diagnosis
  • Myositis* / drug therapy
  • Nitriles*
  • Panniculitis* / diagnosis
  • Panniculitis* / drug therapy
  • Pyrazoles*
  • Pyrimidines*

Substances

  • ruxolitinib
  • Antibodies, Antinuclear
  • Autoantibodies
  • Nitriles
  • Pyrazoles
  • Pyrimidines

Supplementary concepts

  • Antisynthetase syndrome