CYP3A4*22 and bleeding risk in ticagrelor users

Basic Clin Pharmacol Toxicol. 2024 Mar;134(3):311-314. doi: 10.1111/bcpt.13977. Epub 2024 Jan 10.
No abstract available

Keywords: CYP3A4; bleeding; genome-wide association study; pharmacogenetics; ticagrelor.

Publication types

  • Letter

MeSH terms

  • Acute Coronary Syndrome*
  • Clopidogrel
  • Cytochrome P-450 CYP3A
  • Humans
  • Percutaneous Coronary Intervention*
  • Platelet Aggregation Inhibitors / adverse effects
  • Ticagrelor / adverse effects
  • Treatment Outcome

Substances

  • Ticagrelor
  • Cytochrome P-450 CYP3A
  • Platelet Aggregation Inhibitors
  • Clopidogrel
  • CYP3A4 protein, human