BCL11B promotes T-cell acute lymphoblastic leukaemia cell survival via the XRCC5/C11ORF21 axis

Xibao Yu; Yuchen Li; Pengyue Yang; Yan Wang; Xuan Liu; Letong Cai; Jing Lai; Yue Zhang; Xianfeng Zha; Grzegorz Krzysztof Przybylski; Ling Xu; Yangqiu Li

doi:10.1002/ctm2.1580

BCL11B promotes T-cell acute lymphoblastic leukaemia cell survival via the XRCC5/C11ORF21 axis

Clin Transl Med. 2024 Feb;14(2):e1580. doi: 10.1002/ctm2.1580.

Authors

Xibao Yu^{1

2

3}, Yuchen Li^{1

2}, Pengyue Yang^{1

2}, Yan Wang^{1

2}, Xuan Liu^{1

2}, Letong Cai^{1

2}, Jing Lai¹, Yue Zhang¹, Xianfeng Zha⁴, Grzegorz Krzysztof Przybylski⁵, Ling Xu^{1

2}, Yangqiu Li^{1

2}

Affiliations

¹ The First Affiliated Hospital and Institute of Hematology, School of Medicine, Jinan University, Guangzhou, Guangdong, China.
² Key Laboratory for Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, Guangdong, China.
³ Guangzhou Municipality Tianhe Nuoya Bio-Engineering Co. Ltd., Guangzhou 510663, Guangdong, China.
⁴ Department of Clinical Laboratory, First Affiliated Hospital, Jinan University, Guangzhou, Guangdong, China.
⁵ Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Cell Survival / genetics
Humans
Ku Autoantigen
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma* / genetics
Repressor Proteins / metabolism
T-Lymphocytes / metabolism
Transcription Factors*
Tumor Suppressor Proteins / metabolism

Substances

Transcription Factors
Tumor Suppressor Proteins
XRCC5 protein, human
Ku Autoantigen
BCL11B protein, human
Repressor Proteins

Publication types

MeSH terms

Substances

Grants and funding