Colistin - That Was Fun, But Now We're Done

NEJM Evid. 2023 Jan;2(1):EVIDe2200298. doi: 10.1056/EVIDe2200298. Epub 2022 Dec 27.

Abstract

Antimicrobial resistance (AMR) is an increasing global threat with estimates that drug-resistant infections contribute to nearly 5 million deaths worldwide every year.1 In particular, carbapenem-resistant Acinetobacter baumannii (CRAB) is emerging as a challenging pathogen to treat and has been designated by the World Health Organization as a priority pathogen for the development of new antimicrobial agents.2 Studies evaluating the efficacy of therapeutic strategies are vitally important in the fight against drug-resistant A. baumannii and other drug-resistant infections.

Publication types

  • Editorial

MeSH terms

  • Acinetobacter Infections* / drug therapy
  • Acinetobacter baumannii*
  • Anti-Bacterial Agents / therapeutic use
  • Carbapenems / therapeutic use
  • Colistin / therapeutic use
  • Humans
  • Microbial Sensitivity Tests

Substances

  • Colistin
  • Anti-Bacterial Agents
  • Carbapenems