Tissue Factor and COVID-19 Associated Thrombosis

Arterioscler Thromb Vasc Biol. 2024 Mar;44(3):523-529. doi: 10.1161/ATVBAHA.123.320144. Epub 2024 Feb 21.

Abstract

Microbial infections activate the innate and adaptive immune systems.1 Pathogen-associated molecular patterns produced by microbes, such as double-stranded RNA, are detected by PRRs (pattern-recognition receptors), such as toll-like receptor 3, and this leads to the expression of interferons and cytokines.1,2.

Keywords: COVID-19; SARS-CoV-2; extracellular vesicles; thromboplastin; thrombosis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, N.I.H., Extramural

MeSH terms

  • COVID-19* / complications
  • Cytokines / metabolism
  • Humans
  • Immunity, Innate
  • Receptors, Pattern Recognition
  • Thromboplastin*

Substances

  • Thromboplastin
  • Receptors, Pattern Recognition
  • Cytokines