Risk factors for sulfamethoxazole/trimethoprim-induced severe cutaneous adverse reactions

Clin Exp Allergy. 2024 May;54(5):366-368. doi: 10.1111/cea.14470. Epub 2024 Mar 10.

Authors

Kanokkarn Pinyopornpanish^{1

2}, Apinya Chungcharoenpanich¹, Putthapon Teepapan¹, Kunlawat Thadanipon^{3

4}, Chulapha Ruangwattanachok⁵, Pansa Lamrahong⁵, Nattakirana Thongdee¹, Nizchapa Dechapaphapitak¹, Chonlaphat Sukasem^{6

7

8

9

10

11}, Chanamon Pongphaew¹², Thawinee Jantararoungtong^{6

7}, Napatrupron Koomdee^{6

7}, Wannada Laisuan¹

Affiliations

¹ Division of Allergy, Immunology and Rheumatology, Department of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
² Division of Allergy Clinical Immunology, Department of Medicine, Chiangmai University Hospital, Chiangmai, Thailand.
³ Department of Clinical Epidemiology and Biostatistics, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
⁴ Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
⁵ Clinical Pharmacy Section, Pharmacy Division, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
⁶ Division of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Bangkok, Thailand.
⁷ Laboratory for Pharmacogenomics, Clinical Pathology, Somdetch Phra Debharatana Medical Centre, Ramathibodi Hospital, Bangkok, Thailand.
⁸ Pharmacogenomics Clinic, Bumrungrad Genomic Medicine Institute, Bumrungrad International Hospital, Bangkok, Thailand.
⁹ Research and Development Laboratory, Bumrungrad International Hospital, Bangkok, Thailand.
¹⁰ Faculty of Pharmaceutical Sciences, Burapha University, Chonburi, Thailand.
¹¹ Department of Pharmacology and Therapeutics, MRC Centre for Drug Safety Science, Institute of Systems, Molecular, and Integrative Biology, University of Liverpool, Liverpool, UK.
¹² Faculty of Medicine, Ramathibodi Hospital, Bangkok, Thailand.

PMID: 38462790
DOI: 10.1111/cea.14470

No abstract available

Keywords: allergy; co‐trimoxazole; human leukocyte antigen (HLA); severe cutaneous adverse reactions (SCARs); sulfamethoxazole/trimethoprim.

Publication types

Letter

MeSH terms

Adult
Aged
Anti-Bacterial Agents / adverse effects
Drug Eruptions / diagnosis
Drug Eruptions / etiology
Female
Humans
Male
Middle Aged
Risk Factors
Trimethoprim, Sulfamethoxazole Drug Combination* / adverse effects

Substances

Trimethoprim, Sulfamethoxazole Drug Combination
Anti-Bacterial Agents

Grants and funding

Faculty of Medicine Ramathibodi Hospital Mahidol University