1 Institute for Systems and Computer Engineering, Technology and Science (INESC TEC), R. Dr. Roberto Frias, Porto, 4200-465, Porto, Portugal. pedro.d.carneiro@inesctec.pt.
2 Faculty of Engineering, University of Porto (FEUP), R. Dr. Roberto Frias, Porto, 4200-465, Porto, Portugal. pedro.d.carneiro@inesctec.pt.
3 IMP Diagnostics, Praça do Bom Sucesso, 61, sala 808, Porto, 4150-146, Porto, Portugal. diana.felizardo@impdiagnostics.com.
4 Cancer Biology and Epigenetics Group, Research Center of IPO Porto (CI-IPOP) / RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto) / Porto Comprehensive Cancer Center (Porto.CCC), R. Dr. António Bernardino de Almeida 865, Porto, 4200-072, Porto, Portugal. diana.felizardo@impdiagnostics.com.
5 Doctoral Programme in Medical Sciences, School of Medicine and Biomedical Sciences - University of Porto (ICBAS-UP), R. Jorge de Viterbo Ferreira 228, Porto, 4050-313, Porto, Portugal. diana.felizardo@impdiagnostics.com.
6 Institute for Systems and Computer Engineering, Technology and Science (INESC TEC), R. Dr. Roberto Frias, Porto, 4200-465, Porto, Portugal. s.oliveira@nki.nl.
7 Faculty of Engineering, University of Porto (FEUP), R. Dr. Roberto Frias, Porto, 4200-465, Porto, Portugal. s.oliveira@nki.nl.
8 IMP Diagnostics, Praça do Bom Sucesso, 61, sala 808, Porto, 4150-146, Porto, Portugal.
9 Department of Pathology, IPO-Porto, R. Dr. António Bernardino de Almeida 865, Porto, 4200-072, Porto, Portugal.
10 Institute of Pathology, University of Bern, Uni Bern, Murtenstrasse 31, Bern, 3008, Bern, Switzerland.
11 Institute for Systems and Computer Engineering, Technology and Science (INESC TEC), R. Dr. Roberto Frias, Porto, 4200-465, Porto, Portugal.
12 Faculty of Engineering, University of Porto (FEUP), R. Dr. Roberto Frias, Porto, 4200-465, Porto, Portugal.