Real-world evidence in the reassessment of oncology therapies: payer perceptions from five countries

Future Oncol. 2024;20(21):1467-1478. doi: 10.2217/fon-2023-1004. Epub 2024 Apr 4.

Abstract

Aim: This study explored the perceived value of real-world evidence (RWE) in the reassessment of oncology therapies by collecting the perspectives of health technology assessment/payer decision-makers.Materials & methods: A web-based survey was conducted using the Market Access Transformation Rapid Payer Response online portal. 30 participants from France, Germany, Spain, the UK and the USA were recruited based on their expertise.Results: Participants agreed that the most common uses of RWE are to confirm efficacy and safety results from randomized controlled trials and to reevaluate the projected utilization of an oncology therapy. We found variability in other reported uses of RWE.Conclusion: The organizations developing RWE should ensure that their plans recognize the heterogeneity in payer perceptions.

Keywords: oncology; payer; real-world evidence; reassessment; survey.

Plain language summary

A survey from the Market Access Transformation RPR portal queried decision-makers from five countries about the value of real-world evidence in oncology therapy reassessment. Participants agreed that RWE can confirm efficacy/safety and reevaluate utilization, but other uses varied.

MeSH terms

  • Evidence-Based Medicine / methods
  • Evidence-Based Medicine / standards
  • France
  • Germany
  • Humans
  • Medical Oncology* / economics
  • Medical Oncology* / statistics & numerical data
  • Neoplasms* / drug therapy
  • Neoplasms* / therapy
  • Spain
  • Surveys and Questionnaires / statistics & numerical data
  • Technology Assessment, Biomedical
  • United Kingdom
  • United States