Advances in the Surgical Management of Esophageal Cancer

Hematol Oncol Clin North Am. 2024 Jun;38(3):559-568. doi: 10.1016/j.hoc.2024.03.001. Epub 2024 Apr 5.

Abstract

Radical esophagectomy with two or three-field lymphadenectomy remains the mainstay of curative treatment for localized esophageal cancer, often in combination with systemic chemotherapy and/or radiotherapy. In this article, we describe notable advances in the surgical management of esophageal cancer over the past decade that have led to an improvement in both surgical and oncologic outcomes. In addition, we discuss new approaches to surgical management currently under investigation that have the potential to offer further benefits to appropriately selected patients. These incremental breakthroughs primarily include advances in endoscopic and minimally invasive techniques, perioperative management protocols, as well as the application of local therapies, including surgery, to oligometastatic disease.

Keywords: Esophageal cancer; Esophagectomy; Surgery.

Publication types

  • Review
  • Research Support, N.I.H., Extramural

MeSH terms

  • Combined Modality Therapy
  • Disease Management
  • Esophageal Neoplasms* / pathology
  • Esophageal Neoplasms* / surgery
  • Esophageal Neoplasms* / therapy
  • Esophagectomy
  • Humans
  • Lymph Node Excision