Cell migration: Collective cell migration is intrinsically stressful

Heng Wang; Jiong Chen

doi:10.1016/j.cub.2024.02.061

Cell migration: Collective cell migration is intrinsically stressful

Curr Biol. 2024 Apr 8;34(7):R275-R278. doi: 10.1016/j.cub.2024.02.061.

Authors

Heng Wang¹, Jiong Chen²

Affiliations

¹ MOE Key Laboratory of Model Animals for Disease Study, Jiangsu Key Laboratory of Molecular Medicine, State Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center, Medical School of Nanjing University, Nanjing, Jiangsu, 210008, China.
² MOE Key Laboratory of Model Animals for Disease Study, Jiangsu Key Laboratory of Molecular Medicine, State Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center, Medical School of Nanjing University, Nanjing, Jiangsu, 210008, China. Electronic address: chenjiong@nju.edu.cn.

PMID: 38593770
DOI: 10.1016/j.cub.2024.02.061

Abstract

Collective cell migration is a key cellular process in development and disease. A new study reports that ER stress is induced during collective cell migration and an intrinsic mechanism prevents migratory cells from over-reacting to ER stress.

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MeSH terms

Cell Movement*