Variants leading to dysfibrinogenaemia in the fibrinogen α-chain at residue Arg19 are not solely associated with bleeding, but also with thrombotic events-RESPONSE

Br J Haematol. 2024 Jun;204(6):2504. doi: 10.1111/bjh.19431. Epub 2024 Apr 12.

Authors

Radha Ramanan^{1

2

3}, James D McFadyen^{1

2

4}, Andrew C Perkins^{1

2

3}, Huyen A Tran^{1

2}

Affiliations

¹ Department of Haematology, Alfred Hospital, Melbourne, Victoria, Australia.
² Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria, Australia.
³ Department of Pathology, Alfred Hospital, Melbourne, Victoria, Australia.
⁴ Atherothrombosis and Vascular Biology Program, Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.

PMID: 38607668
DOI: 10.1111/bjh.19431

No abstract available

Publication types

Letter

MeSH terms

Afibrinogenemia* / blood
Afibrinogenemia* / genetics
Arginine
Female
Fibrinogen* / genetics
Fibrinogen* / metabolism
Hemorrhage* / etiology
Humans
Male
Thrombosis* / blood
Thrombosis* / etiology

Substances

Fibrinogen
Arginine