Photoinduced decatungstate-catalyzed C(sp3)-H thioetherification by sulfinate salts

Org Biomol Chem. 2024 May 1;22(17):3420-3424. doi: 10.1039/d4ob00394b.

Abstract

Thiols and thioesters play crucial roles in pharmaceuticals, biology, and material science as essential organosulfur compounds. Leveraging readily available and cost-effective inert alkanes through direct thioetherification holds promise for yielding high-value-added products. Herein, we present a photoinduced strategy for sulfur-containing modification of inert alkanes utilizing decatungstate as hydrogen atom transfer reagent, offering a straightforward and practical approach for synthesizing thioethers and thioesters.