Major aphthae are usually located on the dorsum of the tongue, the mucosal surface of the lips and the palate. They are large, round or oval ulcers, with a whitish-grey bed, well-defined borders and erythematous halo. They are very often accompanied by severe pain. Major aphthae can take up to four months to heal, often with a scar. Relapses are possible. We present a case of giant major aphtha that was previously diagnosed as squamous cell carcinoma.
Keywords: aphtha major; pyoderma gangrenosum; squamous cell carcinoma.
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