Does Parkinson's disease affect sleep quality?

Ir J Med Sci. 2024 Aug;193(4):2035-2039. doi: 10.1007/s11845-024-03689-3. Epub 2024 Apr 16.

Abstract

Background: Parkinson's disease (PD) is a common neurodegenerative disease that is linked to several motor and nonmotor symptoms, including sleep disturbances. Patient quality of life has been shown to be disproportionally impacted by disease.

Objectives: To investigate sleep quality among individuals with PD, and to assess the severity of sleep disturbances and their impact on daytime activities.

Subjects and methods: A case‒control with 44 patients with Parkinson's disease and 80 apparently healthy control participants was recruited from several hospitals and clinics. Each participant provided a thorough medical history and underwent a physical examination, and a questionnaire comprising the standard PSQI was used to assess sleep quality. Independent samples t test and Spearman's correlation analysis were used with a p value equal to or less than 0.05 which was considered significant.

Results: The mean global PSQI score was 11.55 ± 4.412 for PD patients and 5.73 ± 3.22 for the control group with significant p value, Sleep latency onset was 75.57 min for PD patients and 22.81 min for the control group with significant p value. There was no significant correlation between age and other sleep-related variables. A total of 86.4% of patients with Parkinson's disease suffered from varying degrees of daytime dysfunction compared to 61.25% of the controls.

Conclusion: Parkinson's disease patients had poorer sleep quality than the controls. Age and sex were not found to be expected as a factor for sleep quality in patients with Parkinson's disease. Daytime dysfunction rates are high in patients with Parkinson's disease.

Keywords: Global PSQI; Parkinson’s disease; Sleep duration; Sleep latency; Sleep quality.

MeSH terms

  • Aged
  • Case-Control Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Parkinson Disease* / complications
  • Parkinson Disease* / physiopathology
  • Quality of Life
  • Sleep Quality*
  • Sleep Wake Disorders / etiology
  • Surveys and Questionnaires