Uncovering chromatin accessibility and cancer diagnostic potential via cell-free DNA utilization

Affiliations

• ¹ Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China; Academy of Biomedical Engineering, Kunming Medical University, Kunming 650500, China.
• ² Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Center of Gastrointestinal Cancer, Peking University Cancer Hospital & Institute, Beijing 100142, China; Department of Gastric Surgery, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou 310022, China.
• ³ Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China; MOE Key Laboratory of Bioinformatics, Tsinghua University, Beijing 100084, China; Peking-Tsinghua-NIBS Joint Graduate Program, Tsinghua University, Beijing 100084, China.
• ⁴ Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Center of Gastrointestinal Cancer, Peking University Cancer Hospital & Institute, Beijing 100142, China.
• ⁵ Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China; MOE Key Laboratory of Bioinformatics, Tsinghua University, Beijing 100084, China.
• ⁶ Guangxi Key Laboratory of Drug Discovery and Optimization, Guilin Medical University, Guilin 541001, China; Department of Anesthesiology, Affiliated Hospital of Guilin Medical University, Guilin 541000, China.
• ⁷ Department of General Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Beijing 100730, China.
• ⁸ Department of Internal Medicine, International Medical Services (IMS), Beijing Tiantan Hospital of Capital Medical University, Beijing 100070, China.
• ⁹ Department of Internal Medicine, International Medical Services (IMS), Beijing Tiantan Hospital of Capital Medical University, Beijing 100070, China. Electronic address: cuipl@aliyun.com.
• ¹⁰ Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China; State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China. Electronic address: pengjunya@pumch.cn.
• ¹¹ Department of General Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Beijing 100730, China; Tsinghua-Peking Joint Center for Life Sciences, Tsinghua University, Beijing 100084, China; State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China. Electronic address: zhao8028@263.net.
• ¹² Department of General Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Beijing 100730, China; State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China; The Islands Healthcare Complex-Macao Medical Center of Peking Union Medical College Hospital, Macao 999078, China. Electronic address: wuwm@pumch.cn.
• ¹³ Guangxi Key Laboratory of Drug Discovery and Optimization, Guilin Medical University, Guilin 541001, China; Key Laboratory of Medical Biotechnology and Translational Medicine, Guilin Medical University, Guilin 541001, China. Electronic address: geneyhh@126.com.
• ¹⁴ Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Center of Gastrointestinal Cancer, Peking University Cancer Hospital & Institute, Beijing 100142, China. Electronic address: buzhaode@cjcrcn.org.
• ¹⁵ Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Center of Gastrointestinal Cancer, Peking University Cancer Hospital & Institute, Beijing 100142, China. Electronic address: jijiafu@hsc.pku.edu.cn.
• ¹⁶ Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China; MOE Key Laboratory of Bioinformatics, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Joint Center for Life Sciences, Tsinghua University, Beijing 100084, China. Electronic address: xlan@tsinghua.edu.cn.