1 Center for Pediatric and Adolescent Medicine, Department of Pediatric Hematology/Oncology, University Medical Center Mainz, 55131 Mainz, Germany.
2 Clinical Development and Human Pain Models, Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, 60596 Frankfurt, Germany.
3 Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Goethe University Frankfurt, University Hospital, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
4 Institute of Legal Medicine, University Hospital, Goethe University, 60590 Frankfurt, Germany.
5 Department of Anesthesiology and Intensive Care, School of Medicine and Health, Technical University of Munich, 81675 Munich, Germany.