Financial hardship and neighborhood socioeconomic disadvantage in long-term childhood cancer survivors

JNCI Cancer Spectr. 2024 Apr 30;8(3):pkae033. doi: 10.1093/jncics/pkae033.

Abstract

Background: Long-term survivors of childhood cancer face elevated risk for financial hardship. We evaluate whether childhood cancer survivors live in areas of greater deprivation and the association with self-reported financial hardships.

Methods: We performed a cross-sectional analysis of data from the Childhood Cancer Survivor Study between 1970 and 1999 and self-reported financial information from 2017 to 2019. We measured neighborhood deprivation with the Area Deprivation Index (ADI) based on current zip code. Financial hardship was measured with validated surveys that captured behavioral, material and financial sacrifice, and psychological hardship. Bivariate analyses described neighborhood differences between survivors and siblings. Generalized linear models estimated effect sizes between ADI and financial hardship adjusting for clinical factors and personal socioeconomic status.

Results: Analysis was restricted to 3475 long-term childhood cancer survivors and 923 sibling controls. Median ages at time of evaluation was 39 years (interquartile range [IQR] = 33-46 years and 47 years (IQR = 39-59 years), respectively. Survivors resided in areas with greater deprivation (ADI ≥ 50: 38.7% survivors vs 31.8% siblings; P < .001). One quintile increases in deprivation were associated with small increases in behavioral (second quintile, P = .017) and psychological financial hardship (second quintile, P = .009; third quintile, P = .014). Lower psychological financial hardship was associated with individual factors including greater household income (≥$60 000 income, P < .001) and being single (P = .048).

Conclusions: Childhood cancer survivors were more likely to live in areas with socioeconomic deprivation. Neighborhood-level disadvantage and personal socioeconomic circumstances should be evaluated when trying to assist childhood cancer survivors with financial hardships.

MeSH terms

  • Adolescent
  • Adult
  • Cancer Survivors* / psychology
  • Cancer Survivors* / statistics & numerical data
  • Child
  • Cross-Sectional Studies
  • Female
  • Financial Stress*
  • Humans
  • Male
  • Middle Aged
  • Neighborhood Characteristics
  • Neoplasms / economics
  • Neoplasms / psychology
  • Poverty
  • Residence Characteristics
  • Self Report
  • Siblings
  • Social Class
  • Socioeconomic Disparities in Health
  • Socioeconomic Factors