Sensory transduction in auditory hair cells-PIEZOs can't touch this

Jeffrey R Holt; Robert Fettiplace; Ulrich Müller

doi:10.1085/jgp.202413585

Sensory transduction in auditory hair cells-PIEZOs can't touch this

J Gen Physiol. 2024 Jun 3;156(6):e202413585. doi: 10.1085/jgp.202413585. Epub 2024 May 10.

Authors

Jeffrey R Holt¹, Robert Fettiplace², Ulrich Müller³

Affiliations

¹ Departments of Otolaryngology and Neurology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.
² Department of Neuroscience, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
³ The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Abstract

In this Viewpoint, Holt, Fettiplace, and Müller weigh the evidence supporting a role for PIEZO and TMC channels in mechanosensory transduction in inner ear hair cells.

MeSH terms

Animals
Hair Cells, Auditory* / physiology
Humans
Ion Channels / metabolism
Mechanotransduction, Cellular / physiology

Substances

Ion Channels

Abstract

MeSH terms

Substances

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