1 From the Divison of Neurology (Abkur, Alhashyan, Algethami), Department of Medicine, University of Toronto, Edmond J. Safra Program in Parkinson's Disease (Abkur, Alhashyan), Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, University Health Network, and from the Depatment of Neurology (Algethami), The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada, from the Department of Medicine (Satti), and the Department of Cardiology (Satti), The Freeman Hospital Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom, and from the Department of Neurology (Di Luca), Washington University in St Louis, St Louis, Missouri, United States, and from Department of Pediatric Neurology (Algethami), National Neuroscience Institute, King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia. Address correspondence and reprint requests to: Dr. Tarig Abkur, Division of Neurology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada. E-mail: Tarig.Abkur@uhn.ca.