The uniqueness of on-demand male contraception

Mol Aspects Med. 2024 Jun:97:101281. doi: 10.1016/j.mam.2024.101281. Epub 2024 May 27.

Abstract

Because nearly half of pregnancies worldwide are unintended, available contraceptive methods are inadequate. Moreover, due to the striking imbalance between contraceptive options available for men compared to the myriad of options available to women, there is an urgent need for new methods of contraception for men. This review summarizes ongoing efforts to develop male contraceptives highlighting the unique aspects particular to on-demand male contraception, where a man takes a contraceptive only when and as often as needed.

Keywords: Nonhormonal male contraception; On-demand contraception; Soluble adenylyl cyclase.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't
  • Research Support, N.I.H., Extramural

MeSH terms

  • Contraception* / methods
  • Contraceptive Agents, Male*
  • Female
  • Humans
  • Male
  • Pregnancy

Substances

  • Contraceptive Agents, Male