Diagnostic and therapeutic challenges with germ cell tumours associated with transverse testicular ectopia and persistent Müllerian duct syndrome

BMJ Case Rep. 2024 May 28;17(5):e260905. doi: 10.1136/bcr-2024-260905.

Abstract

Transverse testicular ectopia (TTE) is an infrequent ectopic testis where both testes descend via the same inguinal canal, located in the same hemiscrotum, and augments the risk of developing testicular tumours. Type II TTE is accompanied by persistent Müllerian duct syndrome, where the Müllerian structures persist for various reasons. Here, we present a case of an adult in his early 30s, who presented with a right testicular swelling and was diagnosed as type II TTE and testicular mixed germ cell tumour after surgery. We could find only 13 similar cases of TTE and testicular tumours in the literature. Our case highlights the importance of clinical acumen with detailed history, meticulous clinical examination, radiological investigations and a detailed pathological examination while dealing with such sporadic presentations.

Keywords: Cancer intervention; Endocrinology; Oncology; Sexual health.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Choristoma / complications
  • Choristoma / diagnosis
  • Choristoma / diagnostic imaging
  • Choristoma / surgery
  • Disorder of Sex Development, 46,XY* / complications
  • Disorder of Sex Development, 46,XY* / diagnosis
  • Disorder of Sex Development, 46,XY* / surgery
  • Humans
  • Male
  • Neoplasms, Germ Cell and Embryonal* / complications
  • Neoplasms, Germ Cell and Embryonal* / diagnosis
  • Neoplasms, Germ Cell and Embryonal* / diagnostic imaging
  • Neoplasms, Germ Cell and Embryonal* / surgery
  • Testicular Neoplasms* / complications
  • Testicular Neoplasms* / diagnosis
  • Testicular Neoplasms* / diagnostic imaging
  • Testicular Neoplasms* / surgery
  • Testis* / abnormalities
  • Testis* / diagnostic imaging
  • Testis* / surgery

Supplementary concepts

  • Persistent Mullerian duct syndrome
  • Testicular Germ Cell Tumor