Poor solubility and stability of rapamycin in aqueous environments

Biomed Pharmacother. 2024 Jul:176:116865. doi: 10.1016/j.biopha.2024.116865. Epub 2024 Jun 7.

Authors

Marijke A J van der Wagt¹, Daan J Touw¹, Bart G J Dekkers²

Affiliations

¹ Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, the Netherlands.
² Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, the Netherlands. Electronic address: b.g.j.dekkers@umcg.nl.

PMID: 38850655
DOI: 10.1016/j.biopha.2024.116865

No abstract available

Publication types

Letter

MeSH terms

Drug Stability*
Sirolimus* / chemistry
Sirolimus* / pharmacology
Solubility*
Water* / chemistry

Substances

Sirolimus
Water