Mucin-rich salivary gland tumors

Semin Diagn Pathol. 2024 Jul;41(4):165-172. doi: 10.1053/j.semdp.2024.06.001. Epub 2024 Jun 8.

Abstract

Salivary gland neoplasms characterized by abundant mucin production are rare but have long been recognized. Due to their scarcity, precise classification has long eluded these mucin-rich tumors. Recent molecular discoveries, however, have shed considerable light on the genetic underpinnings of mucin-rich salivary gland neoplasms. This manuscript will review the most up-to-date information on this fascinating group of salivary gland neoplasms.

Keywords: AKT1; Mucinous adenocarcinoma; Mucoepidermoid carcinoma; Salivary duct carcinoma.

Publication types

  • Review

MeSH terms

  • Biomarkers, Tumor / genetics
  • Humans
  • Mucins* / metabolism
  • Salivary Gland Neoplasms* / genetics
  • Salivary Gland Neoplasms* / pathology

Substances

  • Mucins
  • Biomarkers, Tumor