Centaurea behen leaf extract mediated green synthesized silver nanoparticles as antibacterial and removing agent of environmental pollutants with blood compatible and hemostatic effects

Sci Rep. 2024 Jun 17;14(1):13941. doi: 10.1038/s41598-024-64468-9.

Abstract

The present study focused on evaluating the antibacterial properties, radical scavenging, and photocatalytic activities of Centaurea behen-mediated silver nanoparticles (Cb-AgNPs). The formation of Cb-AgNPs was approved by UV-Vis spectrometry, Fourier-transform infrared spectroscopy, transmission electron microscopy, scanning electron microscopy (SEM), energy dispersive X-ray and X-ray diffraction. The results showed that the obtained AgNPs have a maximum absorbance peak at 450 nm with spherical morphology and an average size of 13.03 ± 5.8 nm. The catalytic activity of the Cb-AgNPs was investigated using Safranin O (SO) solution as a cationic dye model. The Cb-AgNPs performed well in the removal of SO. The coupled physical adsorption/photocatalysis reaction calculated about 68% and 98% degradation of SO dye under solar irradiation. The Cb-AgNPs inhibited the growth of gram-negative or positive bacteria strains and had excellent DPPH radicals scavenging ability (100% in a concentration of 200 µg/ml) as well as a good effect on reducing coagulation time (at concentrations of 200 and 500 µg/mL reduced clotting time up to 3 min). Considering the fact that green synthesized Cb-AgNPs have antioxidant and antibacterial properties and have a good ability to reduce coagulation time, they can be used in wound dressings. As well as these NPs with good photocatalytic activity can be a suitable option for degrading organic pollutants.

Keywords: Antibacterial activity; Catalytic activity; Green synthesis; Hemolytic activity; Silver nanoparticles.

MeSH terms

  • Anti-Bacterial Agents* / chemistry
  • Anti-Bacterial Agents* / pharmacology
  • Centaurea* / chemistry
  • Environmental Pollutants / chemistry
  • Green Chemistry Technology* / methods
  • Hemostatics / chemistry
  • Hemostatics / pharmacology
  • Metal Nanoparticles* / chemistry
  • Microbial Sensitivity Tests
  • Plant Extracts* / chemistry
  • Plant Extracts* / pharmacology
  • Plant Leaves* / chemistry
  • Silver* / chemistry
  • Silver* / pharmacology

Substances

  • Silver
  • Anti-Bacterial Agents
  • Plant Extracts
  • Environmental Pollutants
  • Hemostatics