Metastatic disease after removal of a renal cell carcinoma smaller than 3 cm in a patient with Birt-Hogg-Dubé syndrome, a case report

Fam Cancer. 2024 Nov;23(4):579-582. doi: 10.1007/s10689-024-00408-w. Epub 2024 Jun 20.

L van Riel^{1

2}, C M Kets³, L P van Hest^{4

5}, F H Menko⁶, B G Boerrigter⁷, S M Franken⁸, R M F Wolthuis⁹, H J Dubbink¹⁰, P J Zondervan¹¹, R J A van Moorselaar¹², A C Houweling^{4

5}, I van de Beek⁶

¹ Department of Human Genetics, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands. l.vanriel@amsterdamumc.nl.
² Department of Human Genetics, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands. l.vanriel@amsterdamumc.nl.
³ Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.
⁴ Department of Human Genetics, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
⁵ Department of Human Genetics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
⁶ Department of Clinical Genetics, Netherlands Cancer Institute, Amsterdam, the Netherlands.
⁷ Department of Pulmonary Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
⁸ Department of Dermatology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
⁹ Department of Human Genetics, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
¹⁰ Department of Pathology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
¹¹ Department of Urology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
¹² Department of Urology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.

No abstract available

Keywords: BHD; Birt-Hogg-Dubé syndrome; FLCN; Genetics; Metastasis; Renal cell carcinoma.

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