Peribiliary cysts: uncommon mimickers of hepatic and biliary cystic lesions

Abdom Radiol (NY). 2025 Jan;50(1):24-37. doi: 10.1007/s00261-024-04472-9. Epub 2024 Jul 1.

Abstract

Peribiliary cysts (PC) are dilatations of the extramural peribiliary glands, with a very characteristic imaging pattern in the contexts of hepatobiliary diseases, idiopathic portal hypertension, adult-type polycystic disease of the liver and kidneys, solitary nonparasitic cysts, and systemic infections. The clinical relevance of PC is related to the fact that their presence may indicate underlying pathologies (such as those mentioned above) and may be considered as a potential marker of liver disease progression. Although imaging findings are quite characteristic, recognizing their main differential diagnoses, including malignancies, can be challenging but are essential to avoiding diagnostic errors.

Keywords: Cysts; Hepatobiliary; Peribiliary.

Publication types

  • Review

MeSH terms

  • Bile Duct Diseases / diagnostic imaging
  • Biliary Tract Diseases / diagnostic imaging
  • Cysts* / diagnostic imaging
  • Diagnosis, Differential
  • Humans
  • Liver Diseases* / diagnostic imaging