Hope vs. Hype II: It is time to offer pre-symptomatic genetic testing for GBA and LRRK2 variants

Parkinsonism Relat Disord. 2024 Sep:126:107041. doi: 10.1016/j.parkreldis.2024.107041. Epub 2024 Jun 20.
No abstract available

Keywords: Disease modification; Genetic counseling; Genetic testing; Genetics; Neuroethics; Neurogenetics; Parkinson disease; Predictive testing.

Publication types

  • Letter
  • Editorial

MeSH terms

  • Genetic Testing*
  • Glucosylceramidase* / genetics
  • Humans
  • Leucine-Rich Repeat Serine-Threonine Protein Kinase-2* / genetics
  • Mutation
  • Parkinson Disease / diagnosis
  • Parkinson Disease / genetics
  • Prodromal Symptoms

Substances

  • Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
  • Glucosylceramidase
  • LRRK2 protein, human
  • GBA protein, human