Eosinophilic granuloma of the cervical spine in a young adult: A rare case report

G Lakshmi Prasad; Gopal Krishna; Ameya Kale; Madhu Rajeshwari; Shashank Sharad Kale

doi:10.25259/SNI_262_2024

Eosinophilic granuloma of the cervical spine in a young adult: A rare case report

Surg Neurol Int. 2024 Jun 14:15:198. doi: 10.25259/SNI_262_2024. eCollection 2024.

Authors

G Lakshmi Prasad¹, Gopal Krishna², Ameya Kale³, Madhu Rajeshwari⁴, Shashank Sharad Kale⁵

Affiliations

¹ Department of Neurosurgery, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India.
² Department of Neurosurgery, Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.
³ Department of Neurology, Connecticut University, Connecticut, United States.
⁴ Department of Pathology All India Institute of Medical Sciences, New Delhi, India.
⁵ Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India.

Abstract

Background: Spinal eosinophilic granulomas (EG) are rare tumors, mostly reported in the pediatric age group. They constitute <1% of primary bone neoplasms, and cervical spine involvement is uncommon.

Case description: A 20-year-old male presented with neck pain for a 4-month duration. Six years previously, he had received six cycles of vinblastine for biopsy-proven histiocytosis of an axillary lymph node; this resulted in incomplete remission. Present magnetic resonance/computed tomography (CT) imaging revealed a lytic C2 body lesion with atlantoaxial instability. When the CT-guided biopsy was suggestive of EG, he was managed with definitive surgery and adjuvant radiotherapy.

Conclusion: Cervical spine EG is rare in adults. CT-guided biopsy should confirm the diagnosis and should be followed by definitive surgery and adjuvant radiotherapy.

Keywords: Adults; Cervical spine; Eosinophilic granuloma; Spine.

Publication types

Case Reports