The dual endothelin-1 antagonist aprocitentan alleviates mitochondrial oxidative stress in human cardiac fibroblasts

Eur Heart J Cardiovasc Pharmacother. 2024 Oct 4;10(6):566-568. doi: 10.1093/ehjcvp/pvae050.
No abstract available

Publication types

  • Letter

MeSH terms

  • Cells, Cultured
  • Endothelin A Receptor Antagonists / pharmacology
  • Endothelin Receptor Antagonists / pharmacology
  • Endothelin-1 / metabolism
  • Fibroblasts* / drug effects
  • Fibroblasts* / metabolism
  • Humans
  • Mitochondria, Heart / drug effects
  • Mitochondria, Heart / metabolism
  • Oxidative Stress* / drug effects

Substances

  • Endothelin-1
  • Endothelin A Receptor Antagonists
  • Endothelin Receptor Antagonists