Receipt of Opioid Agonist Treatment in provincial correctional facilities in British Columbia is associated with a reduced hazard of nonfatal overdose in the month following release

PLoS One. 2024 Jul 10;19(7):e0306075. doi: 10.1371/journal.pone.0306075. eCollection 2024.

Abstract

Background: In many jurisdictions, policies restrict access to Opioid Agonist Treatment (OAT) in correctional facilities. Receipt of OAT during incarceration is associated with reduced risk of fatal overdose after release but little is known about the effect on nonfatal overdose. This study aimed to examine the association between OAT use during incarceration and nonfatal overdose in the 30 days following release.

Methods and findings: Using linked administrative healthcare and corrections data for a random sample of 20% of residents of British Columbia, Canada we examined releases from provincial correctional facilities between January 1, 2015 -December 1, 2018, among adults (aged 18 or older at the time of release) with Opioid Use Disorder. We fit Andersen-Gill models to examine the association between receipt of OAT in custody and the hazard of nonfatal following release. We conducted secondary analyses to examine the association among people continuing treatment initiated prior to their arrest and people who initiated a new episode of OAT in custody separately. We also conducted sex-based subgroup analyses. In this study there were 4,738 releases of 1,535 people with Opioid Use Disorder. In adjusted analysis, receipt of OAT in custody was associated with a reduced hazard of nonfatal overdose (aHR 0.55, 95% CI 0.41, 0.74). This was found for prescriptions continued from community (aHR 0.49, 95%CI 0.36, 0.67) and for episodes of OAT initiated in custody (aHR 0.58, 95%CI 0.41, 0.82). The effect was greater among women than men.

Conclusions: OAT receipt during incarceration is associated with a reduced hazard of nonfatal overdose after release. Policies to expand access to OAT in correctional facilities, including initiating treatment, may help reduce harms related to nonfatal overdose in the weeks following release. Differences in the effect seen among women and men indicate a need for gender-responsive policies and programming.

MeSH terms

  • Adolescent
  • Adult
  • Analgesics, Opioid / therapeutic use
  • British Columbia / epidemiology
  • Drug Overdose* / drug therapy
  • Drug Overdose* / epidemiology
  • Drug Overdose* / prevention & control
  • Female
  • Humans
  • Male
  • Middle Aged
  • Opiate Overdose / drug therapy
  • Opiate Overdose / epidemiology
  • Opiate Substitution Treatment / methods
  • Opioid-Related Disorders* / drug therapy
  • Opioid-Related Disorders* / epidemiology
  • Prisoners / statistics & numerical data
  • Prisons / statistics & numerical data
  • Young Adult

Substances

  • Analgesics, Opioid

Grants and funding

Dr. K E McLeod was supported by a Health Systems Impact Doctoral Fellowship from the Canadian Institutes of Health Research. Award number 201904HI8. “The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript”.