Safeguarding Accuracy: The Impact of Interventions on Reducing Blood Culture Contamination

Fareeha Adnan; Nazia Khursheed; Moiz Ahmed Khan; Nazia Parveen

doi:10.1177/2632010X241265857

Safeguarding Accuracy: The Impact of Interventions on Reducing Blood Culture Contamination

Clin Pathol. 2024 Jul 26:17:2632010X241265857. doi: 10.1177/2632010X241265857. eCollection 2024 Jan-Dec.

Authors

Fareeha Adnan¹, Nazia Khursheed¹, Moiz Ahmed Khan¹, Nazia Parveen²

Affiliations

¹ Consultant, Microbiology Department, Indus Hospital & Health Network, Karachi, Pakistan.
² Senior Technologist, Microbiology Department, Indus Hospital & Health Network, Karachi, Pakistan.

Abstract

Introduction: Blood culture is the gold standard for diagnosing bacteremia and direct the physicians to select appropriate antimicrobials. In hospitals, blood culture contamination (BCC) is a common problem that has a detrimental effect on patient outcomes. Hence, we implemented strategies in our tertiary care setup, for training phlebotomists and nurses in proper blood sampling techniques, and assessed their effectiveness in reducing BCC rates.

Methods: This interventional study was conducted at the Indus Hospital, Karachi, Pakistan from 1^st January 2021 to 30^th June 2023. All blood cultures received from different departments of the hospital were included. The 2.5-year study period was divided into pre-intervention and intervention periods, with monthly monitoring of BCC. The BCC data between 1^st January 2021 and 31^st December 2021 was taken as the baseline pre-intervention period and the next 1.5 years comprised the intervention period (1^st January 2022-30^th June 2023). To improve compliance, various strategies were implemented, such as regular training sessions, didactic sessions, and re-competencies.

Results: A total of 86 774 Blood cultures were received from all departments of the hospital, out of which n = 30 672 were received in the pre-intervention period whereas, n = 56 102 were received in the intervention period. Mean BCC rate in the pre-intervention period was found to be 4.6%. However, after the implementation of different measures to reduce BCC, the contamination rate decreased to a mean of 3.1% by the end of the intervention period. Emergency department accounted for the highest proportion of BCC in the pre-intervention and intervention periods.

Conclusion: We decreased BCC in our tertiary care setup by implementing a simple and inexpensive collaborative intervention, and came to the conclusion that the higher incidence of BCC was probably caused by factors unique to the emergency department and provided measures to successfully address them.

Keywords: Blood culture; contamination; intervention; quality improvement.