Development of a deep-learning model for detecting positive tubules during sperm recovery for nonobstructive azoospermia

Reproduction. 2024 Aug 27;168(4):e240181. doi: 10.1530/REP-24-0181. Print 2024 Oct 1.

Abstract

To enhance surgical testicular sperm retrieval outcome for men with nonobstructive azoospermia, a deep-learning model was developed to identify positive seminiferous tubules by labeling 110 images with sperm-containing tubules sampled during microdissection testicular sperm extraction as training and validation data. After training, the model achieved an average precision of 0.60.

MeSH terms

  • Azoospermia* / diagnosis
  • Deep Learning*
  • Humans
  • Male
  • Microdissection
  • Seminiferous Tubules* / pathology
  • Sperm Retrieval*
  • Spermatozoa / physiology
  • Testis / pathology
  • Testis / surgery

Supplementary concepts

  • Azoospermia, Nonobstructive