Current Status and Future Perspective of Onco-Hypertension

Am J Hypertens. 2024 Dec 16;38(1):1-6. doi: 10.1093/ajh/hpae099.

Abstract

Background: Hypertension and cancer are both increasing with age. Recently, the new concept of "Onco-Hypertension" has been proposed to address the mutual risks posed by hypertension and cancer and to provide comprehensive care for patients with these two conditions in an aging society.

Methods: In this review, we provide an overview of the current status and future perspective of the "Onco-Hypertension," including our research findings.

Results: Hypertension and cancer share common risk factors and may be interrelated in pathogenesis: Hypertension is involved in the development of certain cancers, and cancer survivors have a higher incidence of hypertension. With recent advances in cancer therapy, the number of cancer survivors has increased. Cancer survivors not only have a higher risk of incident hypertension but also an increased risk of future cardiovascular events, highlighting the growing importance of comprehensive care.

Conclusions: There exists a diverse array of epidemiological and pathophysiological relationships between hypertension and cancer. It is imperative to move the emerging scientific field of "Onco-Hypertension" forward through relentless research efforts.

Keywords: blood pressure; cancer; cardiovascular disease; hypertension; onco-hypertension; oncology.

Publication types

  • Review

MeSH terms

  • Antihypertensive Agents / therapeutic use
  • Blood Pressure / drug effects
  • Cancer Survivors
  • Humans
  • Hypertension* / epidemiology
  • Hypertension* / physiopathology
  • Hypertension* / therapy
  • Incidence
  • Neoplasms* / complications
  • Neoplasms* / epidemiology
  • Neoplasms* / therapy
  • Prognosis
  • Risk Assessment
  • Risk Factors

Substances

  • Antihypertensive Agents