Nourishing the mind: Fasting for brain health

Sebastian J Hofer; Frank Madeo

doi:10.1016/j.cmet.2024.06.005

Nourishing the mind: Fasting for brain health

Cell Metab. 2024 Aug 6;36(8):1635-1637. doi: 10.1016/j.cmet.2024.06.005.

Authors

Sebastian J Hofer¹, Frank Madeo²

Affiliations

¹ Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Robert-Rössle-Str. 10, 13125 Berlin, Germany; Institute of Molecular Biosciences, NAWI Graz, University of Graz, Humboldtstrasse 50, 8010 Graz, Austria. Electronic address: sebastian.hofer@mdc-berlin.de.
² Institute of Molecular Biosciences, NAWI Graz, University of Graz, Humboldtstrasse 50, 8010 Graz, Austria; BioTechMed-Graz, Graz, Austria; Field of Excellence BioHealth, University of Graz, Graz, Austria. Electronic address: frank.madeo@uni-graz.at.

PMID: 39111281
DOI: 10.1016/j.cmet.2024.06.005

Abstract

Aging and obesity are intertwined in a vicious circle that leads to declining general and brain-specific functions. Kapogiannis and colleagues demonstrate that implementing just 8 weeks of two distinct low-calorie regimes can enhance cognition and biochemical markers of aging in older people with obesity.

MeSH terms

Aging* / physiology
Brain* / metabolism
Caloric Restriction
Cognition / physiology
Fasting* / physiology
Humans
Obesity / metabolism