Can clinicians identify community-acquired pneumonia on ultralow-dose CT? A diagnostic accuracy study

Scand J Trauma Resusc Emerg Med. 2024 Aug 7;32(1):67. doi: 10.1186/s13049-024-01242-w.

Abstract

Background: Without increasing radiation exposure, ultralow-dose computed tomography (CT) of the chest provides improved diagnostic accuracy of radiological pneumonia diagnosis compared to a chest radiograph. Yet, radiologist resources to rapidly report the chest CTs are limited. This study aimed to assess the diagnostic accuracy of emergency clinicians' assessments of chest ultralow-dose CTs for community-acquired pneumonia using a radiologist's assessments as reference standard.

Methods: This was a cross-sectional diagnostic accuracy study. Ten emergency department clinicians (five junior clinicians, five consultants) assessed chest ultralow-dose CTs from acutely hospitalised patients suspected of having community-acquired pneumonia. Before assessments, the clinicians attended a focused training course on assessing ultralow-dose CTs for pneumonia. The reference standard was the assessment by an experienced emergency department radiologist. Primary outcome was the presence or absence of pulmonary opacities consistent with community-acquired pneumonia. Sensitivity, specificity, and predictive values were calculated using generalised estimating equations.

Results: All clinicians assessed 128 ultralow-dose CTs. The prevalence of findings consistent with community-acquired pneumonia was 56%. Seventy-eight percent of the clinicians' CT assessments matched the reference assessment. Diagnostic accuracy estimates were: sensitivity = 83% (95%CI: 77-88), specificity = 70% (95%CI: 59-81), positive predictive value = 80% (95%CI: 74-84), negative predictive value = 78% (95%CI: 73-82).

Conclusion: This study found that clinicians could assess chest ultralow-dose CTs for community-acquired pneumonia with high diagnostic accuracy. A higher level of clinical experience was not associated with better diagnostic accuracy.

Keywords: Antimicrobial stewardship; Community-acquired infections; Community-acquired pneumonia; Diagnostic imaging; Emergency medicine; Ultralow-dose CT.

MeSH terms

  • Aged
  • Clinical Competence
  • Community-Acquired Infections* / diagnosis
  • Community-Acquired Infections* / diagnostic imaging
  • Cross-Sectional Studies
  • Emergency Service, Hospital
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pneumonia* / diagnosis
  • Pneumonia* / diagnostic imaging
  • Radiation Dosage
  • Sensitivity and Specificity
  • Tomography, X-Ray Computed* / methods