The impact of the COVID-19 pandemic on childhood vaccination rates and the role of sociodemographic factors: A cohort study

Vaccine. 2024 Sep 17;42(22):126207. doi: 10.1016/j.vaccine.2024.126207. Epub 2024 Aug 8.

Abstract

Objective: This study examines the impact of the COVID-19 pandemic on both routine and non-routine vaccinations in infants during their initial 18 months of life, concurrently exploring the complex influence of sociodemographic factors.

Methods: A cohort study was conducted, involving 2007 children in two distinct periods: pre-pandemic (January-June 2018) and pandemic (March 2020-May 2021). Participants were classified into two cohorts: 962 children in the 2018 group and 1045 children in the 2020-21 group. Utilizing unconditional logistic regression, the association between vaccination (complete or non-routine) and socioeconomic factors was examined, with adjustments for potential confounding variables such as age, breastfeeding, gestational age, and twins.

Results: The study's analysis reveals that in the post-pandemic period, mothers were three times more likely to opt for non-routine vaccines (95% CI 2.25-4.23). However, no significant alterations were observed in routine vaccination rates. Protective factors for complete vaccination included having an employed mother, higher education, and a medium-to-high income. Conversely, a higher income was associated with a reduced likelihood of complete vaccination (OR 0.34, 95% CI 0.20-0.59).

Conclusion: Contrary to initial expectations, this study concludes that the COVID-19 pandemic did not have a substantial impact on childhood complete vaccination rates. Nevertheless, a noticeable increase in the choice of non-routine vaccination was observed. Sociodemographic factors, such as maternal education, income, and employment status, emerged as key influencers, particularly in the context of deciding on non-routine vaccinations.

Keywords: COVID-19 pandemic; Childhood immunization; Cohort study; Employment status; Infant vaccinations; Maternal education; Non-routine vaccination; Routine vaccination; Sociodemographic factors; Socioeconomic factors.

MeSH terms

  • Adult
  • COVID-19* / epidemiology
  • COVID-19* / prevention & control
  • Cohort Studies
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Mothers / statistics & numerical data
  • Pandemics / prevention & control
  • SARS-CoV-2 / immunology
  • Sociodemographic Factors*
  • Socioeconomic Factors*
  • Vaccination Coverage / statistics & numerical data
  • Vaccination* / statistics & numerical data