Increased Colonic Fluorodeoxyglucose Uptake in Melanosis Coli-A Case Series of Three Patients

Ryo Katsumata; Noriaki Manabe; Maki Ayaki; Tomohiro Tanikawa; Minoru Fujita; Yumika Ono; Hideyo Fujiwara; Mitsuhiko Suehiro; Yasumasa Monobe; Katsuya Kato; Hirofumi Kawamoto; Ken Haruma

doi:10.1016/j.gastha.2021.10.001

Increased Colonic Fluorodeoxyglucose Uptake in Melanosis Coli-A Case Series of Three Patients

Gastro Hep Adv. 2022 Feb 3;1(2):125-128. doi: 10.1016/j.gastha.2021.10.001. eCollection 2022.

Affiliations

¹ Department of General Internal Medicine 2, Kawasaki Medical School General Medical Center, Okayama, Japan.
² Division of Endoscopy and Ultrasonography, Department of Clinical Pathology and Laboratory Medicine, Kawasaki Medical School General Medical Center, Okayama, Japan.
³ Department of Radiology, Kawasaki Medical School General Medical Center, Okayama, Japan.

Abstract

We report 3 Japanese cases with increased colonic 18-fluorodeoxyglucose (FDG) uptake in association with melanosis coli. Case 1: A 56-year-old woman received 18-FDG positron emission tomography (PET) for comprehensive medical checkup. Case 2: A 79-year-old man received FDG-PET for follow-up evaluation for intestinal cancer. Case 3: A 51-year-old woman received FDG-PET for medical checkup. Each showed increased cecal and/or ascending colonic uptake without any colonic wall changes. Colonoscopy detected melanosis coli where FDG uptake was demonstrably increased. Neither malignancy nor inflammatory response was confirmed. Succeeding follow-ups showed neither malignant nor inflammatory lesions in any of the patients.

Keywords: Anthraquinones; Colonoscopy; Fluorodeoxyglucose F 18.

Publication types

Case Reports