Anetoderma in the Setting of a Hematologic Abnormality and COVID-19 Infection

Am J Dermatopathol. 2024 Nov 1;46(11):e104-e105. doi: 10.1097/DAD.0000000000002823. Epub 2024 Aug 14.

Abstract

Anetoderma is an uncommonly reported dermatosis clinically characterized by discrete skin lesions resulting from elastic fiber loss within the dermis. Although primary anetoderma has been considered idiopathic, a range of associated disorders, particularly prothrombotic abnormalities, have been reported. We present a 79-year-old woman with a heterozygous Factor V Leiden mutation who developed anetoderma shortly after COVID-19 infection complicated by a thromboembolic event. Our patient adds to the literature on the occurrence of anetoderma in the setting of infection and/or a prothrombotic disorder.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anetoderma* / pathology
  • COVID-19* / complications
  • Factor V / genetics
  • Female
  • Humans
  • SARS-CoV-2

Substances

  • Factor V
  • factor V Leiden