Identification of the novel HLA-DRB3*03:69 allele by next-generation sequencing

HLA. 2024 Aug;104(2):e15646. doi: 10.1111/tan.15646.

Authors

Isabella Fantini Molinari¹, Anthony Marçal Leão de Oliveira¹, Fernanda Pelisson Massi^{1

2}, Bruna Karina Banin Hirata², Jeane Eliete Laguila Visentainer²

Affiliations

¹ Department of Clinical Analysis and Biomedicine (DAB), Postgraduate Program in Biosciences and Physiopathology (PBF), Laboratory of Immunogenetics at the State University of Maringá (LIG-UEM), Maringá, Paraná, Brazil.
² Department of Basic Health Sciences (DBS), Laboratory of Immunogenetics at the State University of Maringá (LIG-UEM), Maringá, Paraná, Brazil.

PMID: 39148285
DOI: 10.1111/tan.15646

Abstract

The new HLA-DRB3*03:69 allele differs from DRB3*03:01:01:03 by change of C → G in exon 3.

Keywords: Brazil; bone marrow transplantation; high resolution; new allele.

© 2024 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

MeSH terms

Alleles*
Base Sequence
Codon
Exons*
HLA-DRB3 Chains* / genetics
High-Throughput Nucleotide Sequencing* / methods
Histocompatibility Testing* / methods
Humans
Sequence Alignment
Sequence Analysis, DNA / methods

Substances

Codon
HLA-DRB3 Chains