The Dawn of a New Pharmaceutical Epoch: Can AI and Robotics Reshape Drug Formulation?

Adv Healthc Mater. 2024 Nov;13(29):e2401312. doi: 10.1002/adhm.202401312. Epub 2024 Aug 18.

Abstract

Over the last four decades, pharmaceutical companies' expenditures on research and development have increased 51-fold. During this same time, clinical success rates for new drugs have remained unchanged at about 10 percent, predominantly due to lack of efficacy and/or safety concerns. This persistent problem underscores the need to innovate across the entire drug development process, particularly in drug formulation, which is often deprioritized and under-resourced.

Keywords: AI; drug development; drug formulation; machine learning; robotics.

MeSH terms

  • Artificial Intelligence*
  • Drug Compounding* / methods
  • Humans
  • Robotics*