From bean to brain: Coffee, gray matter, and neuroprotection in neurological disorders spectrum

Prog Brain Res. 2024:289:169-180. doi: 10.1016/bs.pbr.2024.06.007. Epub 2024 Jul 8.

Abstract

Coffee is a popular drink enjoyed around the world, and scientists are very interested in studying how it affects the human brain. This chapter looks at lots of different studies to understand how drinking coffee might change the brain and help protect it from neurodegenerative disorders especially like schizophrenia. With the help of available literature a link between the coffee mechanism and neurodegenerative disorders is established in this chapter. Researchers have found that drinking coffee can change the size of certain parts of the brain that control things like thinking and mood. Scientists also study how coffee's ingredients, especially caffeine, can change how the brain works. They think these changes could help protect the brain from diseases. This chapter focuses on how coffee might affect people with schizophrenia as hallucination is caused during and after excess consumption of caffeine. There's still a lot we don't know, but researchers are learning more by studying how different people's brains respond to coffee over time. Overall, this chapter shows that studying coffee and the brain could lead to new ways to help people with brain disorders. This study also draws ideas for future research and ways to help people stay healthy.

Keywords: Caffeine; Coffee; Hallucination; Neurological disorders; Schizophrenia.

Publication types

  • Review

MeSH terms

  • Animals
  • Brain / drug effects
  • Caffeine / administration & dosage
  • Caffeine / pharmacology
  • Coffee*
  • Gray Matter* / drug effects
  • Gray Matter* / pathology
  • Humans
  • Nervous System Diseases / drug therapy
  • Neuroprotection / drug effects
  • Neuroprotection / physiology
  • Neuroprotective Agents / pharmacology
  • Schizophrenia

Substances

  • Coffee
  • Caffeine
  • Neuroprotective Agents