A Case of Fibular Aplasia-Tibial Campomelia-Oligosyndactyly (FATCO) Syndrome Associated With Split Hand/Foot Syndrome With Long Bone Deficiency (SHFLD) and Review of the Literature

Theodora-Eleftheria Deftereou; Vaya R Karapepera; Christina Angelika Alexiadi; Stylianos Tologkos; Vasiliki Papadatou; Georgios Alexiadis; Dimitrios Karamanidis; Lambropoulou Maria

doi:10.7759/cureus.65162

A Case of Fibular Aplasia-Tibial Campomelia-Oligosyndactyly (FATCO) Syndrome Associated With Split Hand/Foot Syndrome With Long Bone Deficiency (SHFLD) and Review of the Literature

Cureus. 2024 Jul 22;16(7):e65162. doi: 10.7759/cureus.65162. eCollection 2024 Jul.

Authors

Theodora-Eleftheria Deftereou¹, Vaya R Karapepera², Christina Angelika Alexiadi¹, Stylianos Tologkos¹, Vasiliki Papadatou¹, Georgios Alexiadis³, Dimitrios Karamanidis⁴, Lambropoulou Maria¹

Affiliations

¹ Laboratory of Histology-Embryology, Democritus University of Thrace, Alexandroupolis, GRC.
² ENT Clinic, General Hospital of Ioannina "G. Hatzikosta", Ioannnina, GRC.
³ Department of Radiology, Private Radiodiagnostic Center, Alexandroupolis, GRC.
⁴ Department of Obstetrics and Gynecology, University General Hospital of Alexandroupolis, Alexandroupolis, GRC.

Abstract

Split hand/foot malformation is a heterogeneous congenital disorder mainly presented with a median cleft of hands or/and feet. It can be associated with long bone aplasia, a syndrome also known as split hand/foot syndrome with long bone deficiency (SHFLD), which is a very rare condition. We report a very rare case of a male fetus with SHFLD syndrome combined with fibular aplasia, tibial campomelia, and oligosyndactyly (FATCO) syndrome. FATCO syndrome is also an extremely infrequent congenital limb defect by itself. Based on our review of the literature, there appears to be no other FATCO case reported in Greece.

Keywords: ectrodactyly; fatco; fibular aplasia; shfld; tibial campomelia.

Publication types

Case Reports